![]() Have you ever wondered what’s inside you? Take a tour around your amazing body and find out what your heart and lungs do, how you see and hear, where food goes and lots more. Used in nearly 60,000 schools, Accelerated Reader provides teachers with an easy and effective way to monitor all forms of guided reading practice. Accelerated Reader (AR) is the world’s most popular reading management software. (“… clearly explained, in an informative way, with lots of jolly illustrations.” Practical Parenting) There is also information on how to look after your teeth, and a little yellow duck to find on each double page. This volume contains three Flip-Flap titles: What happens to your food?, How do your senses work?, and How are babies made?īuy: First Encyclopedia of the Human BodyĪmazing photographs and illustrations with lively text to explain the amazing human body.Ī trip to the dentist is much easier if you know what to expect! With sensitive and humorous illustrations, this book shows small children what happens at the dentist – from the chair that goes up and down to all the dentist’s equipment. Take a look at how you see, hear, smell, taste and touch. Find out what happens to the food that you swallow. Now you can discover the inside view of the amazing human body…with the help of fantastic fold-out flaps. If you’re working with children, whether you are a parent or teacher, consider the following skill set ideas when reading Science books with your child: Preschool or Elementary Unit Study Adventures of the Human Body Lesson Plan Ideas ![]()
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![]() ![]() When completing all transactions, the database instance disconnects all the currently connected users from the database and shuts down. The database instance also does not accept any new transaction after a SHUTDOWN TRANSACTIONAL. This saves the work for all users without requesting them to log off. The SHUTDOWN TRANSACTIONAL waits for all uncommitted transactions to complete before shutting down the database instance. The SHUTDOWN or SHUTDOWN NORMAL is not really practical because you practically cannot wait for all users to come back to their desks and disconnect from the database. ![]() Therefore SHUTDOWN and SHUTDOWN NORMAL commands have the same effect. The NORMAL is the default option if you don’t explicitly specify any option. The SHUTDOWN NORMAL does not require an instance recovery on the next database startup. The database instance will not accept any further database connection. The SHUTDOWN NORMAL option waits for the current users to disconnect from the database before shutting down the database. Let’s examine each option of the SHUTDOWN command. Total of 1 processors activated (4020.89 BogoMIPS).SHUTDOWN ]Ĭode language: SQL (Structured Query Language) ( sql ) NMI watchdog: enabled on all CPUs, permanently consumes one hw-PMU counter. CPU0: AMD Athlon(tm) 64 Processor 3000+ stepping 00 ftrace: allocating 17956 entries in 71 pages Inode-cache hash table entries: 131072 (order: 8, 1048576 bytes) Dentry cache hash table entries: 262144 (order: 9, 2097152 bytes) AppArmor: AppArmor disabled by boot time parameter Calibrating delay loop (skipped), value calculated using timer frequency. Marking TSC unstable due to TSCs unsynchronized please try 'cgroup_disable=memory' option if you don't want memory cgroups Dump stacks of tasks blocking RCU-preempt GP. RCU dyntick-idle grace-period acceleration is enabled. Preemptible hierarchical RCU implementation. SLUB: Genslabs=15, HWalign=64, Order=0-3, MinObjects=0, CPUs=2, Nodes=1 PID hash table entries: 4096 (order: 3, 32768 bytes) Kernel command line: BOOT_IMAGE=/boot/vmlinuz-linux root=UUID=55614e59-14b9-47c5-a609-fd76662e6403 ro systemd.log_level=debug systemd.log_target=kmsg log_buf_len=1M enforcing=0 quiet Built 1 zonelists in Node order, mobility grouping on. ![]() setup_percpu: NR_CPUS:64 nr_cpumask_bits:64 nr_cpu_ids:2 nr_node_ids:1 Booting paravirtualized kernel on bare hardware Using ACPI (MADT) for SMP configuration information ACPI: INT_SRC_OVR (bus 0 bus_irq 15 global_irq 15 high edge) ACPI: INT_SRC_OVR (bus 0 bus_irq 14 global_irq 14 high edge) ACPI: INT_SRC_OVR (bus 0 bus_irq 9 global_irq 9 high level) ACPI: INT_SRC_OVR (bus 0 bus_irq 0 global_irq 2 dfl dfl) IOAPIC: apic_id 2, version 17, address 0xfec00000, GSI 0-23 ACPI: LAPIC_NMI (acpi_id high edge lint) If you got timer trouble try acpi_use_timer_override kernel direct mapping tables up to 0x5ffeffff Base memory trampoline at 96000 size 24576 Aperture from AGP e0000000 size 32 MB (APSIZE 0) Aperture size 4096 MB (APSIZE 0) is not right, using settings from NB Aperture from AGP e0000000 old size 32 MB Command line: BOOT_IMAGE=/boot/vmlinuz-linux root=UUID=55614e59-14b9-47c5-a609-fd76662e6403 ro systemd.log_level=debug systemd.log_target=kmsg log_buf_len=1M enforcing=0 quiet ![]() ![]() "Global Master Award for Distillery Experience" Spirits Business UK "Americas Best Distillery Experience" by The American Distilling Institute "Best Distillery Tour In the World" by Drinks International Magazine UK However, there are great places within walking distance to eat and imbibe. Do you serve food and are there additional drinks for sale?įood is not served and additional drinks are not available for purchase on the tour. Many people often choose to take Uber/Lyft.Ħ. There is a paid lot next to the LA Gun Club and Officine Brera. Be sure to check all signs on the street as some spots are ticketed after 8 PM. Yes, however, parking can be very difficult in the Arts District. NOTE: High heels are unsafe in this environment and are not permitted. There is no dress code, however, due to the rough terrain, flat shoes are recommended. The distillery is for people of ages 21 and up only. Pictures are allowed anywhere on the tour except in the laboratory. You may use your camera, but please, refrain from using your flash when photographing. May I use my camera on the tour and are there any spots off limits? Journeys through the distillery, lab, and surrounding terrain typically take 2 hours.Ģ. We encourage you to have a designated sober driver or use a car service to get you home safe.Appropriate precautions are recommended in advance of your tour. Some medications, including marijuana, can cause undesired effects when combined with high-proof alcohol.Also, the facility can reach temperatures ~85 degrees, so we encourage lighter clothing choices or layers. The tour includes terrain unsuitable for high heels or open-toe shoes.Identification will be required at the distillery gates. You must be 21 years of age to enter a working distillery.IMPORTANT REGULATORY NOTICES, RESTRICTIONS, AND INFORMATION: The distillery was engineered and constructed by the five working partners without use of contractors or outside labor. Set in the Arts District of Los Angeles, the facility is immersive and the laboratory is legendary in the industry. You'll also be guided through the lab to see current experiments and upcoming releases. Tours typically last 90 min-2 hours and include a journey through every step of the spirits-making (and imagining) process, from inception and raw ingredients to the finished product. On your visit, you'll enjoy a 4 - 6 "course" tasting menu with the people who make it. Lost Spirits Distillery is a creative design house & laboratory producing some of the world’s most extreme and unique spirits, including high-ester rums and peated single malts. G ATES WILL BE LOCKED AT THE LISTED TOUR TIME AND LATE ARRIVALS CANNOT BE ACCOMMODATED. Price: 40 dollars (covers the tour and tasting only, dinner is not included) Who: LGBT Bar LA Active/Paid Dues Members If you have any questions please email Madison at Lost Spirits Distillery, Downtown Arts District Madison Fairchild will be your host for this event. Register now as we have limited spaces! Bring your business cards and get ready for a fun kick off to the weekend! It's a great opportunity to meet and socialize with members of the bar in a more intimate way that you cannot always get at large mixers. Registration is for Members of the LGBT Bar LA only. The tour starts at 8 pm sharp - don't be late or be left out! From there we will walk over to a local restaurant for dinner before the tour. ![]() We will gather at the Lost Spirits Distillery in the Arts District at 6:30 pm on September 21st, 2018 (Friday). Finally turns to old cigarette ash as it fades.For the Month of September we are continuing with our intimate Dinner of X gatherings and this month we are doing a distillery tour and tasting event. Medium dry, gently warming spirit with good concentration. ![]() The palate again resembles Anejo Mezcal more than whisky as we know it. Five minutes in the glass the malt starts peaking through. Then almost class Mezcal-like with its exotic, smokey, baked vegetable notes. Tasting note: Deep copper appearance with some fine sediment evident. The result is a slightly sweet, powerful, and densely smokey whiskey. California grown organic barley has been peated with vast quantities of course cut Canadian peat.The intense smoke is balanced by maturation in casks that previously held an exotic botrytised cabernet sauvignon. They bottle at cask strength, release only single cask bottlings, and do not chill-filter.Īt 110 ppm, Leviathan I is one of the three most heavily peated whiskeys in the world. Lost Spirits is a small distillery dedicated to making expressive whiskies inspired by Islay. ![]() ![]() ![]() Magical packet is a broadcast frame which works on OSI Layer 2 where it contains the remote system MAC address and FF or 255 values for data.The first 6 bytes contains “FF FF FF FF FF FF” value and then the MAC address of the target system by repeating 16 times. Magic Packet will trigger the start of a system remotely. When the NIC receives the magical packet the NIC will signal the computer power supply or motherboard to wake-up or boot the system like pressing the power button. The magic packets contains the remote system NIC MAC address where the remote system NIC is only listening to the network in low-power mode even the system is powered down. Wake On Lan (WOL) is ea feature provided the network interface card and motherboard in order to boot a system over a network connection by sending special package which is called as Magic Packet. Wake On LAN is a method that can start the computer from the network. But in some cases, we may need to boot or start the computer from remote by using different techniques. I complied because I wanted to get used to it.Computers are generally started with the power on/off buttons. JimmyFal: Interesting and annoying how Microsoft literally tried to FORCE all us OneNote users off the desktop version an onto the OneNote for Windows 10 app a few years ago. Hopefully, they will speed up the process of this transition into merging the two…Ĭommented on: OneNote's latest feature on Windows will help users enhance productivity It's done a little less elegantly, but when you're in draw mode and go full screen, the same effect happens. ![]() MindHead: OneNote for Windows 10 had this same feature for a while. But MS hates nice looking UI so.Ĭommented on: How to use a video wallpaper on Windows 10 or 11 Both wallpaper and lock screen should offer this. Whether it's a good or bad thing for battery life and you like it or not is irrelevant. Mike Steel: This should be part of the OS. For example, it can be used for overnight backup: automatically wake your PC and run backup software. Wake-on-Lan may be useful in situations where you want your computer to automatically start-up without any user interaction. The app also has Unattended Access support for Wake on Lan on your Windows 11 computer. You can now install the WolOn Android app on your smartphone to remotely power up your PC. You have enabled Wake on LAN on your Windows 11 computer. Finally, restart your PC and you’re done.Here, look for the Wake-on-Magic Packet option and enable it from the Value drop-down menu. Next, move to the Advanced tab and scroll down to the Property window.Be sure to select Allow this device to wake the computer and Only allow a magic packet to wake the computer. Next, navigate to the Power Management tab and enable all options.After following the steps above, find your Ethernet controller from the list of Network Adapters and select the Properties option to the right.Once your device is on, press the Windows key + X key simultaneously and select the Device Manager.After enabling Wake on LAN, save the BIOS configuration and restart your computer. Then, navigate to the BIOS’s Advanced or Power Management tab.To enter the BIOS, you need to press a key (generally the F10, F2, Del, or Esc keys) as soon as your computer boots up. To enable Wake-on-LAN, you must first access your computer’s BIOS.Here's how to set up Wake-On-Lan in Windows 11: ![]() ![]() ![]() Your feedback has been critical in these last stages of development and will continue to be a driver for our team for years to come. We are incredibly proud of the dedication our community has shown throughout CoH-Development. This provides our hard-working team and partners with the necessary time to deliver Company of Heroes 3 in a better overall state. While we know many of you are itching to get your hands on the game, we believe this to be the best decision for Company of Heroes 3, our players and our studio. Nearly a year after Relic Entertainment and Sega announced Company of Heroes 3, the next entry in the beloved World War II real-time strategy series finally has a release date. Relic Entertainment announced today it’s delaying its upcoming real-time strategy title, Company of Heroes 3.Originally scheduled for release on November 11, it’s now launching on February 23. ![]() There still are bugs to squash, pixels to polish, gameplay to adjust and feedback to address.Īs a result, we’ve decided to move the launch date to February 23, 2023. This will give some extra time to polish. The RTS game was originally slated to release on 17 November 2022.Ĭheck out the full statement from the developer below (via Twitter):Īs we approach the November 17 launch date for Company of Heroes 3, our team has decided the game is not quite up to our players’ or our own high standards. Sega and Relic have announced that Company of Heroes 3 has been delayed from the intended November release, and will now launch on 23rd February 2023. A unique feature of Company of Heroes Online was the large number of combinations of hero units, special abilities and doctrinal abilities a player could utilize, giving the potential for diverse and creative strategies.Sega and Relic Entertainment have announced that Company Of Heroes 3 will now be launching for PC on 23 February 2023. ![]() Another departure from mainstream RTS's was the implementation of sector supply whereby the resource income of a player is linked to the sectors under that player's control. Its gameplay placed emphasis on usage of varying degrees of cover together with a destructible terrain. The Korean and American versions featured the entire single-player campaign from the retail release while the Chinese version did not.Ĭompany of Heroes Online was a real-time strategy game which was based on Company of Heroes. Fans have already been able to experience some of the. The game is set to take place once again in WW2, this time, in Italy and some parts of the North African Campaign. Company of Heroes 3 is scheduled to release in November 2022, although the developers have not yet confirmed the official release date. Originally scheduled for release on November 11, it’s now launching on February 23. The Chinese version was co-developed and published by Shanda while the South Korean version was published by WindySoft and developed entirely by Relic Entertainment. Company of Heroes 3 was announced by Relic and Sega in July 2021. Relic Entertainment announced today it’s delaying its upcoming real-time strategy title, Company of Heroes 3. Relic also released a Chinese and a South Korean version of the game. The game uses the same graphics engine as the retail release of Company of Heroes. This is all just tweaking time, apparently, as Relic have. The game had been due to launch next month on November 17th, but Relic say they need extra time for 'bug fixing, balancing, and polishing'. The game has no link with the original Company of Heroes multiplayer system and is a stand-alone game, unlike its predecessors. Upcoming real-time strategy threequel Company Of Heroes 3 has been delayed to February 23rd, 2023, Sega and devs Relic Entertainment have announced. The open beta for the game started on 2 September 2010, and the game was cancelled on March 31st 2011. Company of Heroes Online was a free massively multiplayer online real-time strategy game developed by Relic Entertainment and published by THQ. Company of Heroes 3's release date is currently set for 17th November 2022 when it will release for PC via Steam, and players actually got the chance to play a little bit of it from a previous Pre-Alpha Preview demo that was made available to the public when it was first revealed. ![]() ![]() ![]() Provided expertise on real-time adaptive image processing techniquesġ989 – 1992 Test Director, Systems Engineer, Lockheed Space Systems How are the multi-tasking and adaptive abilities of people supported by the distributed neural architecture, and how does experience combine with genetic and neurochemical factors to adapt neural networks into successful behaviors? Our second objective is to understand how development influences information processing and learning to illuminate how these factors impact human behavior.Ģ006 – present Physical Science Research Associate, CIBSR, Stanford UniversityĢ004 – 2005 Physical Science Research Assoc., Gabrieli Cognitive Neuroscience Lab, Stanford UniversityĢ002 – 2003 Imaging Engineer, Foveon, Inc.ĭeveloped automated quality tests of imaging chips for Sigma digital camerasġ996 – 2002 Manager, Verification and Computer Aided Design,ĭeveloped imaging chips used in Xerox DC 212/214 copiersġ992-1996 Consultant, Hughes Electro-Optical Systems, and Lockheed Systems These activites are computationally complex for even the most simple behaviors. At a deeper level, a functional map represents a "footprint" of underlying neural activities. ![]() How does functional activity in the brain reflect the difference between healthy and mentally impaired populations?Our first objective isto create new methods for accurate fMRI analysis of clinical data to bettercharacterize these populations. Psychiatry and Behavioral Sciences, Stanford University Center for Interdisciplinary Brain Sciences Research ![]() ![]() ![]() Get your free kit 9 Successful Businesses Run by Moms We've created a free 44-page activity book of engaging activities and exercises designed to lead children between the ages of 9-12 through the journey of imagining and developing a business idea. It was my working mom moment of revelation: my daughter was not only unaffected by my being a working woman, but she was encouraging her friends to join her on her own imaginary work day. She asked, “Do you wanna play ‘Let’s Go To The UPS Store?” and then waved her friend over to get into her imaginary car. One Saturday during a playdate, I overheard my daughter talking to her friend, suggesting that they try playing a new game. “I was plagued all day long while working by the thought that I was a terrible mom for sending my firstborn to childcare too soon. Our experiences may be different, but the children of mom entrepreneurs can have upbringings just a rich as my own. Or maybe we’d have just traded crafting sessions for entrepreneurship lessons. If she had owned her own business, maybe we’d have missed out. We were incredibly lucky to have had our mom there all the time. She raised three kids, volunteered for a women’s shelter, led our Brownie troop, organized our bowling league, chaperoned our school trips, sewed costumes for school plays, and still had time to make milk-carton boats and butter tarts and crocheted Christmas ornaments from scratch. Though she didn’t “work” for many years, she was still a working mom – her business was us. My own mother (Hi, Mom!) was, for the majority of my childhood, of the stay-at-home variety. ![]() Similarly, when parents raise a child, they also have no idea what’s coming-minute-to-minute." A Founding Moms meet-up “Ask business owners and they’ll likely tell you that, at any one time, they had no idea what they were doing. Business owners often have to “make it up”, Jill says, employing cunning and resourcefulness to get things done, and learning along the way. So how are they doing it? Easy: moms are made to be entrepreneurs – the skillsets required for each are remarkably similar. “I started it because I was running unrelated businesses and merely wanted to find other women building businesses and raising babies at the same time - because how were they doing it? Apparently I’m not the only one wondering these things.” Jill Salzman She’s the brains behind Founding Moms (her third business venture), a collective of online resources and offline meet-ups that help mom-slash-entrepreneurs connect to build better businesses together. Since I can’t speak from experience, I enlisted the help of Jill Salzman – serial entrepreneur, speaker, podcast host, community rouser, and mom. I try to imagine my own capacity for motherhood: how could I possibly add another thing to my already-hectic life? I don’t have time to shower most days, and the home-cooked-to-takeout ratio leans heavily on the latter.īut moms everywhere are making it happen, simultaneously nurturing small businesses and small humans – both 24/7 jobs. She’s a stay home mom, a student, an artist, a maker, and an entrepreneur. I have watched my best friend make Pad Thai one-handed, the other occupied with a squirming baby, while remaining fully immersed in our conversation. Multitasking gets a bad rap these days, as the kryptonite to mindfulness, but for working moms it’s their lifeblood.īatman v SuperMom? Place your bets, folks. ![]() And they still find time to squabble with each other. A millionaire playboy moonlights as a crime-fighting rodent. A newspaper photographer by day becomes a flying strongman by night. ![]() The superheroes have cornered the market on multi-tasking. ![]() ![]() ![]() This is one of the reasons it’s best not to have more than 6 players, because you otherwise are unlikely to ever determine a winner. If you have 3 opponents, you must correctly match all 3 during one answer phase. To win, a player must reach the “WIN!” space and then correctly match an answer to everyone at the table. The judge moves ahead 2x the number of correct answers. For each correct answer, the player moves ahead two spaces. The players jot down what they think the judge will answer. In this case, the judge jots down their answer. Reversal is played if a player lands on one of the reversal spaces on the board. ![]() ![]() The player whose answer was correctly chosen also moves ahead one spot. The judge often jots down a bit of the answer for memory purposes (to match them later), and then matches each player with an answer.įor each correct or matching answer, the judge is able to move their game piece ahead 1 square. This player reads off the answers in random order. The other players answer the question truthfully by writing on a Loaded Questions answer sheet, then turn in their answers to the person on the right of the judge. Depending on where it lands, they ask one of four different questions (based on category). They roll the die and move their game piece that many tiles. In my experience, children as young as 8 can play, though they might need some prompting or explanations with questions involving certain subjects.Īt the start of each round, one player is the judge. In the instructions, they say it takes about 3 minutes to learn to play. There are rules here.” Needless to say, the game works best if people provide truthful answers, and it could be considered cheating if you don’t. It’s caused several spats, and he’ll say “This isn’t Vietnam. I have a friend whose daughters like to give nonsense or silly answers and it drives their father crazy. The answer can be slightly vague or deceptive, but it should contain the truth. Everyone else answers a question truthfully. Loaded Questions lets you test your knowlege of other players. I’m getting a bit ahead of myself, though. I’ve always been a fan of the Legion of Superheroes, Superman, and Thor, but my favorite character in childhood was Green Lantern–he could do anything. Remember, it’s about our favorite childhood superhero. One friend of ours who will not shut up about Superman and Batman and even the Doom Patrol replied with Ghost Rider, whom he’s never mentioned. For instance, when we had the question “Who was your favorite comic book character in childhood?”, most of the group gave wildly different answers than expected. Not only does it provide a lot of laughs, but you actually learn something about people you might not otherwise know. In my mind, Loaded Question is one of the underrated games on the market. I’ll discuss later why I recommend limiting the number of competitors. It is possible, though not recommended, to play with larger groups. The game was created by Eric Poses for 3 to 6 players. Loaded Questions is a question-based card game from All Things Equal publishing. Loaded Questions Has Added Fun to Many Family Reunions around My Household ![]() ![]() ![]() 2 Here What Are Grooks Grooks were originally created by the Danish poet Piet Hein, (19051996) who wrote over 7000 of them in both the Danish and English languages. The cause of the green stem disorder remains unknown. Green Stem Media NEWEST RELEASES Latter-day Grooks: From the Words and Wisdom of Russell M. Bean leaf beetle, leaf hopper, or stinkbug feeding did not have an effect on the incidence of green stem disorder. BPMV infection did not increase green stem disorder incidence in comparison to controls. A third research approach completed over two growing seasons in field cages showed that green stem disorder developed without BPMV infection. Despite differences in virus infection, including BPMV incidence, 20 of 24 entries had similar green stem disorder incidence at the two locations. A second research approach compared green stem disorder incidence in an identical set of soybean entries planted in two locations with different levels of natural virus infection. According to a chi-square test of independence, the data indicated that green stem disorder was independent of BPMV infection at growth stage R6 (P = 0.98). ![]() Many plants infected with BPMV did not develop green stem disorder, and conversely, many plants that had green stem disorder were not infected with BPMV. The percentage of monitored plants infected with BPMV at growth stage R6 in some fields was higher than the incidence of green stem disorder at harvest maturity. Leaf samples from maturing plants (growth stage R6) were tested by enzyme-linked immunosorbent assay (ELISA) for BPMV. The first research approach surveyed green stem disorder and BPMV in individual plants monitored in several commercial soybean fields during three growing seasons. Three different field research approaches were designed to determine the relationship of green stem disorder to Bean pod mottle virus (BPMV) and other potential factors that may be involved in causing this disorder. Green stem disorder of soybean (Glycine max) is characterized by delayed senescence of stems with normal pod ripening and seed maturation. ![]() ![]() ![]() On the other hand, there is a growing interest in the role of vitamin D to support bone health, and healthcare providers are increasing their use of laboratory tests to assess vitamin D status among the population. Concern has arisen recently that calcium supplementation may be harmful, so some individuals and healthcare providers are reluctant to use calcium supplements. Whereas some studies show that calcium plus vitamin D supplementation reduces the risk of fractures, others show no effect, and one study shows that supplementation may increase the risk. Calcium plus vitamin D supplementation has been widely recommended for the prevention of osteoporosis and subsequent fractures however, recent data have been inconsistent. Although many factors contribute to this debilitating event, the most significant causes are reduction in bone mass, structural deterioration, and increased frequency of falls. The risk of osteoporotic fractures increases with age among individuals aged >50 years. This meta-analysis of RCTs supports the use of calcium plus vitamin D supplements as an intervention for fracture risk reduction in both community-dwelling and institutionalized middle-aged to older adults. A limitation is that this study utilized data from subgroup analysis of the Women’s Health Initiative. Numerous sensitivity and subgroup analyses produced similar summary associations. Meta-analysis of all studies showed that calcium plus vitamin D supplementation produced a statistically significant 15 % reduced risk of total fractures (SRRE, 0.85 95 % confidence interval, 0.73–0.98) and a 30 % reduced risk of hip fractures (SRRE, 0.70 95 % CI, 0.56–0.87). Of the citations retrieved, eight studies including 30,970 participants met criteria for inclusion in the primary analysis, reporting 195 hip fractures and 2231 total fractures. Statistical heterogeneity was assessed using Cochran’s Q test and the I 2 statistic, and potential for publication bias was assessed. ![]() Qualitative and quantitative information was extracted random-effects meta-analyses were conducted to generate summary relative risk estimates (SRREs) for total and hip fractures. RCTs reporting the effect of calcium plus vitamin D supplementation on fracture incidence were selected from English-language studies. MethodsĪ PubMed literature search was conducted for the period from Jthrough July 31, 2015. The aim was to conduct a meta-analysis of randomized controlled trials of calcium plus vitamin D supplementation and fracture prevention in adults. IntroductionĬalcium plus vitamin D supplementation has been widely recommended to prevent osteoporosis and subsequent fractures however, considerable controversy exists regarding the association of such supplementation and fracture risk. Meta-analysis showed a significant 15 % reduced risk of total fractures (summary relative risk estimate, 0.85 95 % confidence interval, 0.73–0.98) and a 30 % reduced risk of hip fractures (SRRE, 0.70 95 % CI, 0.56–0.87). The aim was to meta-analyze randomized controlled trials of calcium plus vitamin D supplementation and fracture prevention. ![]() |
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